| SC Paderborn 07 – 1899 Hoffenheim |
20. Sep 17:30 |
| SC Paderborn 07 – VfB Stuttgart |
10. Oct 13:30 |
| Werder Bremen – SC Paderborn 07 |
17. Oct 13:30 |
| SC Paderborn 07 – Hamburger SV |
24. Oct 13:30 |
| Borussia Mönchengladbach – SC Paderborn 07 |
31. Oct 14:30 |
| SC Paderborn 07 – Eintracht Frankfurt |
07. Nov 14:30 |
| Bayer Leverkusen – SC Paderborn 07 |
21. Nov 14:30 |
| SC Paderborn 07 – FC Schalke 04 |
28. Nov 14:30 |
| Bayern München – SC Paderborn 07 |
05. Dec 14:30 |
| SC Paderborn 07 – SV Elversberg |
12. Dec 14:30 |
| FC Augsburg – SC Paderborn 07 |
19. Dec 14:30 |
| SC Paderborn 07 – RB Leipzig |
09. Jan 14:30 |
| Union Berlin – SC Paderborn 07 |
12. Jan 19:30 |
| SC Paderborn 07 – 1. FC Köln |
16. Jan 14:30 |
| SC Paderborn 07 – FSV Mainz 05 |
23. Jan 14:30 |
| SC Freiburg – SC Paderborn 07 |
30. Jan 14:30 |
| SC Paderborn 07 – Borussia Dortmund |
06. Feb 14:30 |
| 1899 Hoffenheim – SC Paderborn 07 |
13. Feb 14:30 |
| VfB Stuttgart – SC Paderborn 07 |
20. Feb 14:30 |
| SC Paderborn 07 – Werder Bremen |
27. Feb 14:30 |
| Hamburger SV – SC Paderborn 07 |
02. Mar 19:30 |
| SC Paderborn 07 – Borussia Mönchengladbach |
06. Mar 14:30 |
| Eintracht Frankfurt – SC Paderborn 07 |
13. Mar 14:30 |
| SC Paderborn 07 – Bayer Leverkusen |
20. Mar 14:30 |
| FC Schalke 04 – SC Paderborn 07 |
03. Apr 13:30 |
| SC Paderborn 07 – Bayern München |
10. Apr 13:30 |
| SV Elversberg – SC Paderborn 07 |
17. Apr 13:30 |
| SC Paderborn 07 – FC Augsburg |
24. Apr 13:30 |
| RB Leipzig – SC Paderborn 07 |
08. May 13:30 |
| SC Paderborn 07 – Union Berlin |
15. May 13:30 |
| 1. FC Köln – SC Paderborn 07 |
22. May 13:30 |
